Encapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions

Encapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions
Their pure capabilities in intercellular communication render extracellular vesicles (EV) extremely engaging for drug supply purposes. Nonetheless, the loading effectivity of current strategies to include notably hydrophilic low molecular weight medicine of biomedical curiosity is basically unexplored, as is the influence these strategies might have on the intrinsic structural and organic vesicle properties.
Right here, completely different strategies are exploited to include hydrophilic non-membrane permeable compounds into stem cell-derived small EV, and to evaluate the vesicle traits after the completely different loading processes. When evaluating a number of strategies head-to-head, the loading capability will increase within the order saponin ≤ sonication < fusion < freeze-thawing ≤ osmotic shock.
Curiously, the structural and organic capabilities of small EV are depending on the utilized encapsulation course of, with the purposeful properties being altered at a higher extent. Due to this fact, the significance of together with further characterization parameters to probe alterations of the organic performance of small EV is clearly demonstrated. Right here, freeze-thawing and notably the osmotic shock have confirmed to be probably the most acceptable strategies for EV loading, as they obtain a excessive drug encapsulation and but protect the investigated structural and organic vesicle traits.

Conformationally versatile core-bearing detergents with a hydrophobic or hydrophilic pendant: Impact of pendant polarity on detergent conformation and membrane protein stability

Membrane protein buildings present atomic degree perception into important biochemical processes and facilitate protein structure-based drug design. Nonetheless, the inherent instability of those bio-macromolecules exterior lipid bilayers hampers their structural and purposeful examine. Detergent micelles can be utilized to solubilize and stabilize these membrane-inserted proteins in aqueous resolution, thereby enabling their downstream characterizations.
Membrane proteins encapsulated in detergent micelles are likely to denature and combination over time, highlighting the necessity for growth of recent amphiphiles efficient for protein solubility and stability. On this work, we current newly-designed maltoside detergents containing a pendant chain hooked up to a glycerol-decorated tris(hydroxylmethyl)methane (THM) core, designated GTMs. One set of the GTMs has a hydrophobic pendant (ethyl chain; E-GTMs), and the opposite set has a hydrophilic pendant (methoxyethoxylmethyl chain; M-GTMs) positioned within the hydrophobic-hydrophilic interfaces.
 Encapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions
The 2 units of GTMs displayed profoundly completely different behaviors by way of detergent self-assembly and protein stabilization efficacy. These behaviors primarily come up from the polarity distinction between two pendants (ethyl and methoxyethoxylmethyl chains) that ends in a big variation in detergent conformation between these units of GTMs in aqueous media. The ensuing excessive hydrophobic density within the detergent micelle inside is probably going accountable for enhanced efficacy of the M-GTMs for protein stabilization in comparison with the E-GTMs and a gold customary detergent DDM.
A consultant GTM, M-GTM-O12, was more practical for protein stability than some not too long ago developed detergents together with LMNG. That is the primary case examine investigating the impact of pendant polarity on detergent geometry that correlates with detergent efficacy for protein stabilization.

An azine-based polymer derived hierarchically porous N-doped carbon for hydrophilic dyes elimination

On this examine, a novel hierarchically porous N-doped carbon (HPNC) materials was efficiently ready by soft-templating technique. The industrial triblock copolymer of Pluronic F127 and a polyazine derived from hydrazine hydrate & glyoxal have been used as comfortable template and precursor, respectively. The obtained supplies have been totally characterised and examined as a sorbent for the elimination of hydrophilic dyes of Methylene blue (MB), Fundamental Fuchsin (BF), Eosin Y (EY) and Rhodamine B (RB) from their aqueous effluents.
Based on the characterization outcomes, the synthesized materials of HPNC-1000 offered thick fibrous morphology with micron dimension in diameter, hierarchically porous construction with floor space of 1853 m2/g, pore quantity of 1.59 cm3/g and nitrogen content material of 4.5 wt%. Adsorption-desorption investigation reveals that synergistic impact of hydrophobic interplay and hydrogen-bonding formation of the dye molecules with the sorbent was most pronounced within the adsorptions. The utmost adsorption capacities for MB, BF, EY and RB reached 0.83, 0.92, 1.23 and 1.83 mmol g-1, respectively. The adsorption processes effectively fitted by the pseudo first-order kinetic mannequin and the Liu’s isotherm. The sorbent will be regenerated by above 90% of the preliminary adsorption effectivity after six regeneration cycles.

Evaluation of Aqueous Extraction Strategies on Extractable Natural Matter and Hydrophobic/Hydrophilic Fractions of Virgin Forest Soils

The evaluation of water-extractable natural matter utilizing an autoclave can present helpful data on bodily, chemical, and organic adjustments throughout the soil. The current examine used virgin forest soils from Chini Forest Reserve, Langkawi Island, and Kenyir Forest Reserve (Malaysia), extracted utilizing completely different extraction strategies.
The dissolved natural carbon (DOC), complete dissolved nitrogen (TDN), complete dissolved phosphorus (TDP), and ammonium-nitrate content material have been greater within the autoclave remedies, as much as 3.0, 1.3, 1.2, and 1.Four occasions greater than by pure extraction (extracted for 24 h at room temperature). General, the best extractable DOC, TDN, TDP, ammonium and nitrate may very well be seen underneath autoclaved situations 121 °C 2×, as much as 146.74 mg C/L, 8.97 mg N/L, 0.23 mg P/L, 5.43 mg N mg/L and three.47 N mg/L, respectively. The soil extracts grew to become barely acidic with a better temperature and longer length.

Cartilage RNA Isolation Kit

K2031010 1 kit
EUR 419
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA Isolation Kit

P-9100 50 samples
EUR 347.25
Description: The best epigenetics products

Glass Beads 0.1mm RNase Free

GB01-RNA 1pack
EUR 96
Description: Glass beads. 0.1mm. 4mL. RNase free.

Glass Beads 0.5mm RNase Free

GB05-RNA 1pack
EUR 96
Description: Glass beads. 0.5mm. 4mL. RNase free.

Stainless Steel Beads 0.2mm RNase Free

SSB02-RNA 1pack
EUR 121
Description: Stainless steel beads. 0.2mm. 4mL. RNase free.

Stainless Steel Beads 0.5mm RNase Free

SSB05-RNA 1pack
EUR 121
Description: Stainless steel beads. 0.5mm. 4mL. RNase free.

Stainless Steel Beads 1.6mm RNase Free

SSB16-RNA 1pack
EUR 128
Description: Stainless steel beads. 1.6mm. 4mL. RNase free.

Stainless Steel Beads 3.2mm RNase Free

SSB32-RNA 1pack
EUR 177
Description: Stainless steel beads. 3.2mm. 10mL. RNase free.

Stainless Steel Beads 4.8mm RNase Free

SSB48-RNA 1pack
EUR 177
Description: Stainless steel beads. 4.8mm. 10mL. RNase free.

Stainless Steel Beads 6.0mm RNase Free

SSB60-RNA 1pack
EUR 179
Description: Stainless steel beads. 6.0mm. 10mL. RNase free.

Zirconium Oxide Beads 0.15mm RNase Free

ZrOB015-RNA 1pack
EUR 106
Description: Fused Zirconium Oxide beads . 0.15mm. 4mL. RNase-free.

Zirconium Oxide Beads 0.5mm RNase Free

ZrOB05-RNA 1pack
EUR 106
Description: Zirconium Oxide beads . 0.5mm. 4mL. RNase-free.

Zirconium Oxide Beads 1.0mm RNase Free

ZrOB10-RNA 1pack
EUR 107
Description: Zirconium Oxide beads . 1.0mm. 4mL. RNase-free.

Zirconium Oxide Beads 2.0mm RNase Free

ZrOB20-RNA 1pack
EUR 107
Description: Zirconium Oxide beads . 2.0mm. 4mL. RNase-free.

Total RNA Isolation Kit II

FATRS--001 100 preps
EUR 308

Total RNA Isolation Kit II

FATRS--050 50 preps
EUR 216

Easy3-Plant RNA Isolation Kit

FYG502-100P 100 Preps Ask for price

Easy3-Plant RNA Isolation Kit

FYG502-500P 500 Preps Ask for price

Total RNA Isolation Kit (Tissue)

P-9102 50 samples
EUR 347.25
Description: reagents widely cited

Total RNA Isolation Kit (Plant)

P-9104 50 samples
EUR 347.25
Description: kits suitable for this type of research

Rapid Plant RNA Isolation Kit

PT4191 50Preps
EUR 79.69
  • Product category: Molecular Biology Kits/RNA - Extraction/Plant

Rapid Bacteria RNA Isolation Kit

BS8625 50Preps
EUR 79.69
  • Product category: Molecular Biology Kits/RNA - Extraction/Bacteria

Rapid Blood RNA Isolation Kit

BT4182 10Preps
EUR 81.97
  • Product category: Molecular Biology Kits/RNA - Extraction/Blood

Rapid Blood RNA Isolation Kit

BT4183 50Preps
EUR 164.19
  • Product category: Molecular Biology Kits/RNA - Extraction/Blood

Rapid Blood RNA Isolation Kit

BT4184 250preps
EUR 506.75
  • Product category: Molecular Biology Kits/RNA - Extraction/Blood

Stainless Steel UFO Beads 3.5mm RNase Free

SSUFO35-RNA 1pack
EUR 189
Description: Stainless steel UFO beads. 3.5mm. 10mL. RNase free.

Stainless Steel UFO Beads 5.6mm RNase Free

SSUFO56-RNA 1pack
EUR 190
Description: Stainless steel UFO beads. 5.6mm. 10mL. RNase free.

VAHTS RNA Clean Beads

N412-01 5 ml
EUR 239

VAHTS RNA Clean Beads

N412-02 40 ml
EUR 413

VAHTS RNA Clean Beads

N412-03 450 ml
EUR 4050

Stainless Steel Beads 0.9 - 2.0mm blend RNase Free

SSB14B-RNA 1pack
EUR 128
Description: Stainless steel beads. 0.9 - 2.0mm. 4mL. RNase free.

RNA-easy Isolation Reagent

R701-01 100 ml
EUR 168

RNA-easy Isolation Reagent

R701-02 200 ml
EUR 212

Green RNA Lysis Kit 50

GREENE1-RNA 50pack
EUR 180
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RNA Lysis Kit 250

GREENE5-RNA 250pack
EUR 571
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Navy RNA Lysis Kit 50

NAVYE1-RNA 50pack
EUR 198
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RNA Lysis Kit 250

NAVYE5-RNA 250pack
EUR 651
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Pink RNA Lysis Kit 50

PINKE1-RNA 50pack
EUR 178
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 250

PINKE5-RNA 250pack
EUR 561
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 50

REDE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 250

REDE5-RNA 250pack
EUR 622
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 50

YELLOWE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 250

YELLOWE5-RNA 250pack
EUR 624
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E GREEN RNA Lysis Kit 100

GREEN5E100-RNA 100pack
EUR 386
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

5E GREEN RNA Lysis Kit 20

GREEN5E20-RNA 20pack
EUR 138
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 50

GREENR1-RNA 50pack
EUR 184
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 250

GREENR5-RNA 250pack
EUR 587
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

5E Navy RNA Lysis Kit 100

NAVY5E100-RNA 100pack
EUR 453
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

5E Navy RNA Lysis Kit 20

NAVY5E20-RNA 20pack
EUR 153
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 50

NAVYR1-RNA 50pack
EUR 202
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 250

NAVYR5-RNA 250pack
EUR 666
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

5E PINK RNA Lysis Kit 100

PINK5E100-RNA 100pack
EUR 380
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E PINK RNA Lysis Kit 20

PINK5E20-RNA 20pack
EUR 136
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 50

PINKR1-RNA 50pack
EUR 181
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 250

PINKR5-RNA 250pack
EUR 576
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 100

RED5E100-RNA 100pack
EUR 429
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 20

RED5E20-RNA 20pack
EUR 148
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 50

REDR1-RNA 50pack
EUR 195
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 250

REDR5-RNA 250pack
EUR 638
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 50

YELLOWR1-RNA 50pack
EUR 199
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 250

YELLOWR5-RNA 250pack
EUR 656
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Soil RNA Isolation Mini Kit (50prep)

FASRK-001 50 preps
EUR 150

Soil RNA Isolation Mini Kit (100prep)

FASRK-100 100 preps
EUR 187

Broad Range Total RNA Isolation Kit

K1341050 1 kit
EUR 266
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Stainless Steel Beads 11mm RNase Free

SSB110-25-RNA 25pack
EUR 278
Description: Stainless steel beads. 11mm. Pack of 25. RNase free.

FastPure Cell/Tissue Total RNA Isolation Kit

RC101 50 rxn
EUR 229

PureXtract RNAsol RNA Isolation Solution, LS

R6103-120 2X60ml
EUR 286

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)

P101NGS NULL
EUR 0

FastPure Plant Total RNA Isolation Kit (Polysaccharides/Polyphenolics-Rich)

RC401 50 rxn
EUR 236

Mitochondria Isolation Kit

AR0156 1 kit
EUR 106

miRNA Isolation Kit

FAMIK--001 Rxns: 100
EUR 332
Description: Contents of the kit:
  • Rxns:100Lysis
  • Buffer-10 ml
  • Acid-Phenol-10 ml
  • RNA Column and Collection Tube-100 sets
  • Wash Buffer-10 ml
  • Release Buffer-0.5 ml

miRNA Isolation Kit

FAMIK--002 Rxns: 50
EUR 223

miRNA Isolation Kit

FYG304-100P 100 Preps Ask for price

Microsome Isolation Kit

K249-50
EUR 528

Preadipocyte Isolation Kit

K583-5
EUR 533

MicroRNA Isolation Kit

KS341025 1 kit
EUR 256
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Endosome Isolation Kit

P528 NULL
EUR 0

ExoQuick Exosome Isolation and RNA Purification kit (for Serum and Plasma)

EQ806A-1 20 preps
EUR 554

ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media)

EQ806TC-1 10 preps
EUR 554

Exorose Beads

EXOB-100 100 ml
EUR 106

Exorose Beads

EXOB-25 25 ml
EUR 58

Exorose Beads

EXOB-250 250 ml
EUR 188

Latex Beads

abx291003-1L 1 L
EUR 2332
  • Shipped within 2 months.

Bulk Beads

D1131-01 1 PC
EUR 238.13
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1131-05 1 PC
EUR 238.13
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1131-10 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-01TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-05TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-10TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-15TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-30TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-60 1 PC
EUR 241.61
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1133-28 1 PC
EUR 93.71
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Cell Mitochondria Isolation Kit

abx090630-50100tests 50-100 tests
EUR 258
  • Shipped within 5-10 working days.

Tissue Mitochondria Isolation Kit

abx090631-50100assays 50-100 assays
EUR 258
  • Shipped within 5-10 working days.

Apoptotic Cell Isolation Kit

55R-1349 30 units
EUR 729
Description: Apoptotic Cell Isolation Kit for use in the research laboratory

Mitochondrial DNA Isolation Kit

55R-1361 50 assays
EUR 825
Description: Mitochondrial DNA Isolation Kit for use in the research laboratory

Genomic DNA Isolation Kit

55R-1362 50 assays
EUR 385
Description: Genomic DNA Isolation Kit for use in the research laboratory

ExoPure? Isolation Kit   (Urine)

K1240-10
EUR 697

ExoPure? Isolation Kit   (Urine)

K1240-2
EUR 403

Mitochondrial DNA Isolation Kit

K2117-50 50 assays
EUR 599

Genomic DNA Isolation Kit

K2118-50 50 assays
EUR 321

Mitochondrial DNA Isolation Kit

K280-50
EUR 588

Genomic DNA Isolation Kit

K281-50
EUR 272

Apoptotic Cell Isolation Kit

K258-30
EUR 468

Yeast Nuclei Isolation Kit

K289-50
EUR 392

Yeast Mitochondria Isolation Kit

K259-50
EUR 419

Lipopolysaccharide (LPS) Isolation Kit

K438-10
EUR 278

Serum DNA Isolation Kit

K5018100 1 kit
EUR 360

Saliva DNA Isolation Kit

K5011050 1 kit
EUR 256

Urine DNA Isolation Kit

K5011150 1 kit
EUR 256

Stool DNA Isolation Kit

K5011250 1 kit
EUR 256

Lipid Droplet Isolation Kit

MET-5011 50 preps
EUR 415
Description: Lipid droplets are lipid rich organelles found in the adipose tissue of eukaryotes. They function to regulate the hydrolysis and storage of neutral lipids and serve as storage for cholesterol and acyl-glycerols. Lipid droplets have also been associated with inflammatory responses, obesity, atherosclerosis, and cancer.

Refill Glass Beads

B1201-BEAD 1 PC
EUR 117.78
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

V5 agarose beads

AE029-100ul 100 ul Ask for price

V5 agarose beads

AE029-200ul 200 ul
EUR 228

V5 agarose beads

AE029-20ul 20 ul Ask for price

V5 agarose beads

AE029-50ul 50 ul Ask for price

Streptavidin Magnetic Beads

HY-K0208 5 mL
EUR 538

Glass Beads 0.1mm

GB01 1pack
EUR 108
Description: Glass beads. 0.1mm. 1 lb. Non-sterile.

Glass Beads 0.5mm

GB05 1pack
EUR 103
Description: Glass beads. 0.5mm. 1 lb. Non-sterile.

Glass Beads 1.0mm

GB10 1pack
EUR 103
Description: Glass beads. 1.0mm. 1 lb. Non-sterile.

Thrombin Sepharose Beads

7925-1
EUR 218

Thrombin Sepharose Beads

7925-25
EUR 1762

Thrombin Sepharose Beads

7925-5
EUR 697

Plasmin Sepharose Beads

7926-1
EUR 218

Plasmin Sepharose Beads

7926-25
EUR 1762

Plasmin Sepharose Beads

7926-5
EUR 697

Urokinase Sepharose Beads

7927-1
EUR 218

Urokinase Sepharose Beads

7927-25
EUR 1762

Urokinase Sepharose Beads

7927-5
EUR 697

Immobilized Catalase Beads

7931-1
EUR 153

Immobilized Catalase Beads

7931-10
EUR 588

Calmodulin-Sepharose Beads

7934-1
EUR 153

Calmodulin-Sepharose Beads

7934-10
EUR 479

Calmodulin-Sepharose Beads

7934-5
EUR 338

Streptavidin-Sepharose Beads

6565-10
EUR 697

Streptavidin-Sepharose Beads

6565-100 Ask for price

Streptavidin-Sepharose Beads

6565-2
EUR 229

Streptavidin-Sepharose Beads

6565-5
EUR 403

EZEnrich? Polyubiquitin Beads

6568-300
EUR 370

Control Magnetic Beads

M1302-1
EUR 98

RanBP1 Agarose Beads

STA-421 400 µg
EUR 572
Description: RanBP1 Agarose Beads selectively pull down the active form of Ran. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

Sodium hydroxide, Beads

SB6789 500g
EUR 61.01
  • Product category: Biochemicals/Adsorbents/Drying Agents/Adsorbents

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Circulating Nuleic Acid Isolation Kit

FACFK-050 50 preps
EUR 491

Circulating Nuleic Acid Isolation Kit

FACFK-100 100 preps
EUR 825

Easy3-Total NucleicAcid Isolation Kit

FYG504-100ML 100 ml Ask for price

Easy3-Total NucleicAcid Isolation Kit

FYG504-500ML 500 ml Ask for price

Exo-Urine EV Isolation Kit

EXOU100A-1 2 x 5 reactions
EUR 551

ExoPure? Isolation Kit   (Cell Media)

K1237-10
EUR 664

ExoPure? Isolation Kit   (Cell Media)

K1237-2
EUR 392

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-10
EUR 697

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-2
EUR 392

ExoPure? Isolation Kit   (Bio Fluids)

K1241-10
EUR 697

ExoPure? Isolation Kit   (Bio Fluids)

K1241-2
EUR 403

Apoptotic DNA Ladder Isolation Kit

K170-50
EUR 468

Apoptotic DNA Ladder Isolation Kit

K2045-50 50 assays
EUR 502

EZExtract? Core Histone Isolation Kit

K234-100
EUR 262

Cell Surface Protein Isolation Kit

K295-10
EUR 501

Org Frontier? Chloroplast Isolation Kit

K468-10
EUR 555

OrgFrontier? Plasma Membrane Isolation Kit

K414-10
EUR 566

Bacterial Genomic DNA Isolation Kit

K309-100
EUR 376

Whole Blood DNA Isolation Kit

K528-100
EUR 376

Exosome Isolation kit (for urine)

P120L NULL
EUR 0

Exosome Isolation kit (for urine)

P120S NULL
EUR 0

FitAmp Gel DNA Isolation Kit

P-1007 100 Samples
EUR 270.4
Description: The best epigenetics products

FitAmp Urine DNA Isolation Kit

P-1017 100 Samples
EUR 395.1
Description: kits suitable for this type of research

ChromaFlash Chromatin Isolation & Shearing Kit

P-2023 100 Preperations
EUR 270.4
Description: kits suitable for this type of research

Detergent-Free Nuclei Isolation Kit

P524-2 NULL
EUR 0

Detergent-Free Nuclei Isolation Kit

P524-20 NULL
EUR 0

Detergent-Free Nuclei Isolation Kit

P524-80 NULL
EUR 0

Lysosome Isolation Kit (20 tests)

P534 NULL
EUR 0

Mouse Brain Microvessel Isolation Kit

P750-4 NULL
EUR 0

XCF Exosomal DNA Isolation Kit

XCF200A-1 20 rxn
EUR 386
  • Category: Exosome

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PSEUDOMONAS ISOLATION AGAR

P16-114-10kg 10 kg
EUR 1715

PSEUDOMONAS ISOLATION AGAR

P16-114-2kg 2kg
EUR 412

PSEUDOMONAS ISOLATION AGAR

P16-114-500g 500 g
EUR 148

PSEUDOMONAS ISOLATION BROTH

P16-115-10kg 10 kg Ask for price

PSEUDOMONAS ISOLATION BROTH

P16-115-2Kg 2 Kg Ask for price

PSEUDOMONAS ISOLATION BROTH

P16-115-500g 500 g Ask for price

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

Orange Lysis Kit 50

ORANGEE1-RNA 50pack
EUR 165
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange Lysis Kit 250

ORANGEE5-RNA 250pack
EUR 537
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 50

ORANGER1-RNA 50pack
EUR 169
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 250

ORANGER5-RNA 250pack
EUR 554
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Anti-Flag magnetic beads

B26101 1 mL
EUR 483
Description: Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification.

Anti-Flag magnetic beads

B26102 5 mL
EUR 1452
Description: Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification.

Anti-HA magnetic beads

B26201 1 mL
EUR 483
Description: Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification.

Anti-HA magnetic beads

B26202 5 mL
EUR 1452
Description: Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification.

Anti-Myc magnetic beads

B26301 1 mL
EUR 483
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Anti-Myc magnetic beads

B26302 5 mL
EUR 1452
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Calibration Beads for MoFlo

B28479
EUR 289
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Anti-HA Magnetic Beads

HY-K0201 1 mL
EUR 279

Protein A Magnetic Beads

HY-K0203 1 mL
EUR 124

Protein G Magnetic Beads

HY-K0204 5 mL
EUR 371

Anti-Flag Magnetic Beads

HY-K0207 1 mL
EUR 475

Size Selection DNA Beads

20-abx298001
  • EUR 217.00
  • EUR 398.00
  • EUR 1386.00
  • 1 ml
  • 5 ml
  • 60 ml
  • Shipped within 5-10 working days.

Protein A Magnetic Beads

6507-1
EUR 262

Protein G Magnetic Beads

6517-1
EUR 262
Comparable developments have been noticed within the humic and nonhumic substances, the place several types of soil extract remedies influenced the concentrations of the fractions. Totally different soil extraction strategies can present additional particulars, thus widening the applying of soil extracts, particularly in microbes.

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